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Role of Muscle c-Jun NH(2)-Terminal Kinase 1 in Obesity-Induced Insulin Resistance

Obesity caused by feeding of a high-fat diet (HFD) is associated with an increased activation of c-Jun NH(2)-terminal kinase 1 (JNK1). Activated JNK1 is implicated in the mechanism of obesity-induced insulin resistance and the development of metabolic syndrome and type 2 diabetes. Significantly, Jnk...

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Autors principals: Sabio, Guadalupe, Kennedy, Norman J., Cavanagh-Kyros, Julie, Jung, Dae Young, Ko, Hwi Jin, Ong, Helena, Barrett, Tamera, Kim, Jason K., Davis, Roger J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798290/
https://ncbi.nlm.nih.gov/pubmed/19841069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01162-09
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