Mammalian Target of Rapamycin (mTOR) Induces Proliferation and De-Differentiation Responses to Three Coordinate Pathophysiologic Stimuli (Mechanical Strain, Hypoxia, and Extracellular Matrix Remodeling) in Rat Bladder Smooth Muscle

Maladaptive bladder muscle overgrowth and de-differentiation in human bladder obstructive conditions is instigated by coordinate responses to three stimuli: mechanical strain, tissue hypoxia, and extracellular matrix remodeling.(1,2) Pathway analysis of genes induced by obstructive models of injury...

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Bibliografiske detaljer
Main Authors: Aitken, Karen J., Tolg, Cornelia, Panchal, Trupti, Leslie, Bruno, Yu, Jeffery, Elkelini, Mohamed, Sabha, Nesrin, Tse, Derrick J., Lorenzo, Armando J., Hassouna, Magdy, Bägli, Darius J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2010
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797892/
https://ncbi.nlm.nih.gov/pubmed/20019183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.080834
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