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Targeting Human Epidermal Growth Factor Receptor Signaling with the Neuregulin's Heparin-binding Domain
A major limitation in biopharmaceutical development is selectively targeting drugs to diseased tissues. Growth factors and viruses have solved this problem by targeting tissue-specific cell-surface heparan sulfates. Neuregulin (NRG), a growth factor important in both nervous system development and c...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797281/ https://ncbi.nlm.nih.gov/pubmed/19717564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032714 |
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