Identifying targets for preventing epilepsy using systems biology

Por Loeb, Jeffrey A.
Publicado em 2011

Neurotrophins Induce Neuregulin Release through Protein Kinase Cδ Activation

Por Esper, Raymond M., Loeb, Jeffrey A.
Publicado em 2009

COALESCENCE OF DEEP AND SUPERFICIAL EPILEPTIC FOCI INTO LARGER DISCHARGE UNITS IN ADULT RAT NEOCORTEX

Por SERAFINI, RUGGERO, ANDRADE, RODRIGO, LOEB, JEFFREY A.
Publicado no Neuroscience (2015)

Critical Period of Axoglial Signaling between Neuregulin-1 and Brain-Derived Neurotrophic Factor Required for Early Schwann Cell Survival and Differentiation

Por Ma, Zhenzhong, Wang, Jiajing, Song, Fei, Loeb, Jeffrey A.
Publicado em 2011

Aberrant Neuregulin1 Signaling in Amyotrophic Lateral Sclerosis

Por Song, Fei, Chiang, Pohung, Wang, Jiajing, Ravits, John, Loeb, Jeffrey A.
Publicado em 2012

Rapid transient isoform-specific neuregulin1 transcription in motor neurons is regulated by neurotrophic factors and axon-target interactions

Por Wang, Jiajing, Hmadcha, Abdelkrim, Zakarian, Vaagn, Song, Fei, Loeb, Jeffrey A.
Publicado no Mol Cell Neurosci (2015)

Targeting Human Epidermal Growth Factor Receptor Signaling with the Neuregulin's Heparin-binding Domain

Por Ma, Zhenzhong, li, Qunfang, An, Haiqian, Pankonin, Mark S., Wang, Jiajing, Loeb, Jeffrey A.
Publicado em 2009

Layer-Specific CREB Target Gene Induction in Human Neocortical Epilepsy

Por Beaumont, Thomas L., Yao, Bin, Shah, Aashit, Kapatos, Gregory, Loeb, Jeffrey A.
Publicado em 2012

Complexity of trophic factor signaling in experimental autoimmune encephalomyelitis: differential expression of neurotrophic and gliotrophic factors

Por Song, Fei, Bandara, Manoj, Deol, Harvinder, Loeb, Jeffrey A., Benjamins, Joyce, Lisak, Robert P.
Publicado em 2013

Following Nerve Injury Neuregulin-1 Drives Microglial Proliferation and Neuropathic Pain via the MEK/ERK Pathway

Por Calvo, Margarita, Zhu, Ning, Grist, John, Ma, Zhenzhong, Loeb, Jeffrey A, Bennett, David L H
Publicado em 2011

Activity-Dependent Human Brain Coding/Noncoding Gene Regulatory Networks

Por Lipovich, Leonard, Dachet, Fabien, Cai, Juan, Bagla, Shruti, Balan, Karina, Jia, Hui, Loeb, Jeffrey A.
Publicado em 2012

The Tanapoxvirus 15L Protein Is a Virus-Encoded Neuregulin That Promotes Viral Replication in Human Endothelial Cells

Por Jeng, David, Ma, Zhenzhong, Barrett, John W., McFadden, Grant, Loeb, Jeffrey A., Essani, Karim
Publicado em 2013

Accuracy of cDNA microarray methods to detect small gene expression changes induced by neuregulin on breast epithelial cells

Por Yao, Bin, Rakhade, Sanjay N, Li, Qunfang, Ahmed, Sharlin, Krauss, Raul, Draghici, Sorin, Loeb, Jeffrey A
Publicado em 2004

Neuregulin-ErbB Signaling Promotes Microglial Proliferation and Chemotaxis Contributing to Microgliosis and Pain after Peripheral Nerve Injury

Por Calvo, Margarita, Zhu, Ning, Tsantoulas, Christoforos, Ma, Zhenzhong, Grist, John, Loeb, Jeffrey A., Bennett, David L. H.
Publicado em 2010

Electrical, Molecular and Behavioral Effects of Interictal Spiking in the Rat

Por Barkmeier, Daniel T., Senador, Danielle, Leclercq, Karine, Pai, Darshan, Hua, Jing, Boutros, Nash N., Kaminski, Rafal M., Loeb, Jeffrey A.
Publicado em 2012

High inter-reviewer variability of spike detection on intracranial EEG addressed by an automated multi-channel algorithm

Por Barkmeier, Daniel T., Shah, Aashit K., Flanagan, Danny, Atkinson, Marie D., Agarwal, Rajeev, Fuerst, Darren R., Jafari-Khouzani, Kourosh, Loeb, Jeffrey A.
Publicado em 2011

WONOEP appraisal: new genetic approaches to study epilepsy

Por Rossignol, Elsa, Kobow, Katja, Simonato, Michele, Loeb, Jeffrey A., Grisar, Thierry, Gilby, Krista L., Vinet, Jonathan, Kadam, Shilpa D., Becker, Albert J.
Publicado em 2014

Epilepsy Therapy Development: Technical and Methodological Issues in Studies with Animal Models

Por Galanopoulou, Aristea S., Kokaia, Merab, Loeb, Jeffrey A., Nehlig, Astrid, Pitkänen, Asla, Rogawski, Michael A., Staley, Kevin J., Whittemore, Vicky H., Dudek, F. Edward
Publicado em 2013

Predicting novel histopathological microlesions in human epileptic brain through transcriptional clustering

Por Dachet, Fabien, Bagla, Shruti, Keren-Aviram, Gal, Morton, Andrew, Balan, Karina, Saadat, Laleh, Valyi-Nagy, Tibor, Kupsky, William, Song, Fei, Dratz, Edward, Loeb, Jeffrey A.
Publicado no Brain (2015)

Finding a better drug for epilepsy: Preclinical screening strategies and experimental trial design

Por Simonato, Michele, Löscher, Wolfgang, Cole, Andrew J., Dudek, F. Edward, Engel, Jerome, Kaminski, Rafal M., Loeb, Jeffrey A., Scharfman, Helen, Staley, Kevin J., Velíšek, Libor, Klitgaard, Henrik
Publicado em 2012