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Fibril Fragmentation Enhances Amyloid Cytotoxicity

Fibrils associated with amyloid disease are molecular assemblies of key biological importance, yet how cells respond to the presence of amyloid remains unclear. Cellular responses may not only depend on the chemical composition or molecular properties of the amyloid fibrils, but their physical attri...

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Main Authors: Xue, Wei-Feng, Hellewell, Andrew L., Gosal, Walraj S., Homans, Steve W., Hewitt, Eric W., Radford, Sheena E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797196/
https://ncbi.nlm.nih.gov/pubmed/19808677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049809
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