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Fibril Fragmentation Enhances Amyloid Cytotoxicity

Fibrils associated with amyloid disease are molecular assemblies of key biological importance, yet how cells respond to the presence of amyloid remains unclear. Cellular responses may not only depend on the chemical composition or molecular properties of the amyloid fibrils, but their physical attri...

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Détails bibliographiques
Auteurs principaux: Xue, Wei-Feng, Hellewell, Andrew L., Gosal, Walraj S., Homans, Steve W., Hewitt, Eric W., Radford, Sheena E.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797196/
https://ncbi.nlm.nih.gov/pubmed/19808677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049809
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