Employing a Recombinant HLA-DR3 Expression System to Dissect Major Histocompatibility Complex II-Thyroglobulin Peptide Dynamism: A GENETIC, BIOCHEMICAL, AND REVERSE IMMUNOLOGICAL PERSPECTIVE

Previously, we have shown that statistical synergism between amino acid variants in thyroglobulin (Tg) and specific HLA-DR3 pocket sequence signatures conferred a high risk for autoimmune thyroid disease (AITD). Therefore, we hypothesized that this statistical synergism mirrors a biochemical interac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jacobson, Eric M., Yang, Heyi, Menconi, Francesca, Wang, Rong, Osman, Roman, Skrabanek, Luce, Li, Cheuk Wun, Fadlalla, Mohammed, Gandhi, Alisha, Chaturvedi, Vijaya, Smith, Eric P., Schwemberger, Sandy, Osterburg, Andrew, Babcock, George F., Tomer, Yaron
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2009
विषय:
Protein Structure and Folding
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797193/
https://ncbi.nlm.nih.gov/pubmed/19776016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041574
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