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Molecular Basis of Glucagon-like Peptide 1 Docking to Its Intact Receptor Studied with Carboxyl-terminal Photolabile Probes

The glucagon-like peptide 1 (GLP1) receptor is a member of Family B G protein-coupled receptors and represents an important drug target for type 2 diabetes. Despite recent solution of the structure of the amino-terminal domain of this receptor and that of several close family members, understanding...

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Detalles Bibliográficos
Main Authors: Chen, Quan, Pinon, Delia I., Miller, Laurence J., Dong, Maoqing
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797184/
https://ncbi.nlm.nih.gov/pubmed/19815559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038109
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