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Predictive Computational Models of Substrate Binding by a Nucleoside Transporter
Transporters play a vital role in both the resistance mechanisms of existing drugs and effective targeting of their replacements. Melarsoprol and diamidine compounds similar to pentamidine and furamidine are primarily taken up by trypanosomes of the genus Trypanosoma brucei through the P2 aminopurin...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797173/ https://ncbi.nlm.nih.gov/pubmed/19808668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049726 |
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