Mediator of DNA Damage Checkpoint 1 (MDC1) Regulates Mitotic Progression

Human mediator of DNA damage checkpoint 1 (hMDC1) is an essential component of the cellular response to DNA double strand breaks. Recently, hMDC1 has been shown to associate with a subunit of the anaphase-promoting complex/cyclosome (APC/C) (Coster, G., Hayouka, Z., Argaman, L., Strauss, C., Friedle...

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Detalhes bibliográficos
Main Authors: Townsend, Kelly, Mason, Helen, Blackford, Andrew N., Miller, Edward S., Chapman, J. Ross, Sedgwick, Garry G., Barone, Giancarlo, Turnell, Andrew S., Stewart, Grant S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797164/
https://ncbi.nlm.nih.gov/pubmed/19826003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009191
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