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Ligand Effects on Cross-linking Support a Conformational Mechanism for Serotonin Transport

Serotonin transporter (SERT) is responsible for the re-uptake of 5-hydroxytryptamine (5-HT) from the synaptic cleft after release from serotonergic neurons. We show here that cysteine residues at positions in transmembranes 1 and 3 of SERT, like the corresponding positions in the γ-aminobutyric acid...

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Detalhes bibliográficos
Main Authors: Tao, Zhen, Zhang, Yuan-Wei, Agyiri, Alice, Rudnick, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797150/
https://ncbi.nlm.nih.gov/pubmed/19837674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.071977
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