An experimental assessment of in silico haplotype association mapping in laboratory mice

BACKGROUND: To assess the utility of haplotype association mapping (HAM) as a quantitative trait locus (QTL) discovery tool, we conducted HAM analyses for red blood cell count (RBC) and high density lipoprotein cholesterol (HDL) in mice. We then experimentally tested each HAM QTL using published cro...

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Autori principali: Burgess-Herbert, Sarah L, Tsaih, Shirng-Wern, Stylianou, Ioannis M, Walsh, Kenneth, Cox, Allison J, Paigen, Beverly
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Research article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797012/
https://ncbi.nlm.nih.gov/pubmed/20003225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-10-81
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