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Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice

To identify genetic loci influencing lipid levels, we performed quantitative trait loci (QTL) analysis between inbred mouse strains MRL/MpJ and SM/J, measuring triglyceride levels at 8 weeks of age in F2 mice fed a chow diet. We identified one significant QTL on chromosome (Chr) 15 and three suggest...

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Detalhes bibliográficos
Main Authors: Leduc, Magalie S., Hageman, Rachael S., Verdugo, Ricardo A., Tsaih, Shirng-Wern, Walsh, Kenneth, Churchill, Gary A., Paigen, Beverly
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151687/
https://ncbi.nlm.nih.gov/pubmed/21622629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M011130
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