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A Bayesian Framework for Inference of the Genotype–Phenotype Map for Segregating Populations

Complex genetic interactions lie at the foundation of many diseases. Understanding the nature of these interactions is critical to developing rational intervention strategies. In mammalian systems hypothesis testing in vivo is expensive, time consuming, and often restricted to a few physiological en...

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Autori principali: Hageman, Rachael S., Leduc, Magalie S., Korstanje, Ron, Paigen, Beverly, Churchill, Gary A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070524/
https://ncbi.nlm.nih.gov/pubmed/21242536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.123273
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