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A Bayesian Framework for Inference of the Genotype–Phenotype Map for Segregating Populations

Complex genetic interactions lie at the foundation of many diseases. Understanding the nature of these interactions is critical to developing rational intervention strategies. In mammalian systems hypothesis testing in vivo is expensive, time consuming, and often restricted to a few physiological en...

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Detalhes bibliográficos
Main Authors: Hageman, Rachael S., Leduc, Magalie S., Korstanje, Ron, Paigen, Beverly, Churchill, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070524/
https://ncbi.nlm.nih.gov/pubmed/21242536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.123273
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