An experimental assessment of in silico haplotype association mapping in laboratory mice

BACKGROUND: To assess the utility of haplotype association mapping (HAM) as a quantitative trait locus (QTL) discovery tool, we conducted HAM analyses for red blood cell count (RBC) and high density lipoprotein cholesterol (HDL) in mice. We then experimentally tested each HAM QTL using published cro...

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Main Authors: Burgess-Herbert, Sarah L, Tsaih, Shirng-Wern, Stylianou, Ioannis M, Walsh, Kenneth, Cox, Allison J, Paigen, Beverly
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797012/
https://ncbi.nlm.nih.gov/pubmed/20003225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-10-81
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