An experimental assessment of in silico haplotype association mapping in laboratory mice

BACKGROUND: To assess the utility of haplotype association mapping (HAM) as a quantitative trait locus (QTL) discovery tool, we conducted HAM analyses for red blood cell count (RBC) and high density lipoprotein cholesterol (HDL) in mice. We then experimentally tested each HAM QTL using published cro...

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Main Authors: Burgess-Herbert, Sarah L, Tsaih, Shirng-Wern, Stylianou, Ioannis M, Walsh, Kenneth, Cox, Allison J, Paigen, Beverly
格式: Artigo
語言:Inglês
出版: BioMed Central 2009
主題:
Research article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797012/
https://ncbi.nlm.nih.gov/pubmed/20003225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-10-81
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