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Proteotoxic stress increases nuclear localization of ataxin-3
Spinocerebellar ataxia type 3 (SCA3)/Machado Joseph disease results from expansion of the polyglutamine domain in ataxin-3 (Atx3). Atx3 is a transcriptional co-repressor, as well as a deubiquitinating enzyme that appears to function in cellular pathways involved in protein homeostasis. In this study...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796889/ https://ncbi.nlm.nih.gov/pubmed/19843543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp482 |
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