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Synthesis and anti-Hantaan virus activity of N(1)-3-fluorophenyl-inosine
As part of an ongoing effort to develop new antiviral nucleoside analogs, our interest was drawn to N(1)-aryl purines as a novel structural class and potential scaffold for drug discovery. Herein, we describe the synthesis of N(1)-3-fluorophenyl-inosine (FPI) and N(1)-3-fluorophenyl-hypoxanthine (FP...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796853/ https://ncbi.nlm.nih.gov/pubmed/19501259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2009.03.007 |
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