Synthesis and anti-Hantaan virus activity of N(1)-3-fluorophenyl-inosine

As part of an ongoing effort to develop new antiviral nucleoside analogs, our interest was drawn to N(1)-aryl purines as a novel structural class and potential scaffold for drug discovery. Herein, we describe the synthesis of N(1)-3-fluorophenyl-inosine (FPI) and N(1)-3-fluorophenyl-hypoxanthine (FP...

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Autori principali: Chung, Dong-Hoon, Strouse, J. Jacob, Sun, Yanjie, Arterburn, Jeffrey B., Parker, William B., Jonsson, Colleen B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796853/
https://ncbi.nlm.nih.gov/pubmed/19501259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2009.03.007
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