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Targeting acidic diseased tissue: New technology based on use of the pH (Low) Insertion Peptide (pHLIP)

We discuss a peptide that targets cells in the acidic tissues that result from a range of pathological states, including tumours, and that can also translocate cell-impermeable cargo molecules across cell membranes in a pH-dependent manner. The technology is based on the interactions of a water-solu...

詳細記述

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書誌詳細
主要な著者: ANDREEV, OLEG A., ENGELMAN, DONALD M., RESHETNYAK, YANA K.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796806/
https://ncbi.nlm.nih.gov/pubmed/20037661
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