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Regulation of the Metastasis Suppressor Gene MKK4 in Ovarian Cancer

OBJECTIVES: MKK4 is a metastasis suppressor that is downregulated in some ovarian cancers. We sought to investigate whether promoter methylation, loss of heterozygosity, or changes in phosphorylation are involved in MKK4 dysregulation during ovarian carcinogenesis. METHODS: Bisulfite sequencing was...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Spillman, Monique A., Lacy, Judith, Murphy, Susan K., Whitaker, Regina S., Grace, Lisa, Teaberry, Vanessa, Marks, Jeffrey R., Berchuck, Andrew
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796629/
https://ncbi.nlm.nih.gov/pubmed/17276500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2006.12.017
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