Regulation of the Metastasis Suppressor Gene MKK4 in Ovarian Cancer

OBJECTIVES: MKK4 is a metastasis suppressor that is downregulated in some ovarian cancers. We sought to investigate whether promoter methylation, loss of heterozygosity, or changes in phosphorylation are involved in MKK4 dysregulation during ovarian carcinogenesis. METHODS: Bisulfite sequencing was...

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Main Authors: Spillman, Monique A., Lacy, Judith, Murphy, Susan K., Whitaker, Regina S., Grace, Lisa, Teaberry, Vanessa, Marks, Jeffrey R., Berchuck, Andrew
格式: Artigo
語言:Inglês
出版: 2007
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796629/
https://ncbi.nlm.nih.gov/pubmed/17276500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2006.12.017
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