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Regulation of the Metastasis Suppressor Gene MKK4 in Ovarian Cancer

OBJECTIVES: MKK4 is a metastasis suppressor that is downregulated in some ovarian cancers. We sought to investigate whether promoter methylation, loss of heterozygosity, or changes in phosphorylation are involved in MKK4 dysregulation during ovarian carcinogenesis. METHODS: Bisulfite sequencing was...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Spillman, Monique A., Lacy, Judith, Murphy, Susan K., Whitaker, Regina S., Grace, Lisa, Teaberry, Vanessa, Marks, Jeffrey R., Berchuck, Andrew
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796629/
https://ncbi.nlm.nih.gov/pubmed/17276500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2006.12.017
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