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Regulation of the Metastasis Suppressor Gene MKK4 in Ovarian Cancer
OBJECTIVES: MKK4 is a metastasis suppressor that is downregulated in some ovarian cancers. We sought to investigate whether promoter methylation, loss of heterozygosity, or changes in phosphorylation are involved in MKK4 dysregulation during ovarian carcinogenesis. METHODS: Bisulfite sequencing was...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796629/ https://ncbi.nlm.nih.gov/pubmed/17276500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2006.12.017 |
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