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Targeting the Transforming Growth Factor-β Signaling Pathway in Human Cancer
The transforming growth factor-β (TGF-β) signaling pathway plays a pivotal role in diverse cellular processes. TGF-β switches its role from tumor suppressor in normal or dysplastic cells to a tumor promoter in advanced cancers. It is widely believed that Smad-dependent pathway is involved in TGF-β t...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796203/ https://ncbi.nlm.nih.gov/pubmed/20001556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543780903382609 |
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