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Regulation of nitric oxide signaling by thrombospondin-1: implications for anti-angiogenic therapies
In addition to long term regulation of angiogenesis, angiogenic growth factor signaling through nitric oxide (NO) acutely controls blood flow and hemostasis. Inhibition of this pathway may account for the hypertensive and prothrombotic side effects of vascular endothelial growth factor antagonists c...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796182/ https://ncbi.nlm.nih.gov/pubmed/19194382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2561 |
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