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THROMBOSPONDIN-1 INHIBITS NITRIC OXIDE SIGNALING VIA CD36 BY INHIBITING MYRISTIC ACID UPTAKE

Although CD36 is generally recognized to be an inhibitory signaling receptor for thrombospondin-1 (TSP1), the molecular mechanism for transduction of this signal remains unclear. Based on evidence that myristic acid and TSP1 each modulate endothelial cell nitric oxide signaling in a CD36-dependent m...

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Detalhes bibliográficos
Main Authors: Isenberg, Jeff S., Jia, Yifeng, Fukuyama, Julia, Switzer, Christopher H., Wink, David A., Roberts, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430148/
https://ncbi.nlm.nih.gov/pubmed/17416590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701638200
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