Identification of iGb3 and iGb4 in melanoma B16F10-Nex2 cells and the iNKT cell-mediated antitumor effect of dendritic cells primed with iGb3

BACKGROUND: CD1d-restricted iNKT cells are protective against murine melanoma B16F10-Nex2 growing subcutaneously in syngeneic C57Bl/6 mice as inferred from the fast tumor development in CD1d-KO in comparison with wild type animals. CD1d glycoproteins are related to the class I MHC molecules, and are...

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Detalhes bibliográficos
Main Authors: Dias, Bianca R, Rodrigues, Elaine G, Nimrichter, Leonardo, Nakayasu, Ernesto S, Almeida, Igor C, Travassos, Luiz R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795753/
https://ncbi.nlm.nih.gov/pubmed/19968878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-116
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