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A New Schizosaccharomyces pombe Chronological Lifespan Assay Reveals that Caloric Restriction Promotes Efficient Cell Cycle Exit and Extends Longevity

We describe a new chronological lifespan (CLS) assay for the yeast Schizosaccharomyces pombe. Yeast CLS assays monitor the loss of cell viability in a culture over time, and this new assay shows a continuous decline in viability without detectable regrowth until all cells in the culture are dead. Th...

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Detalhes bibliográficos
Main Authors: Chen, Bo-Ruei, Runge, Kurt W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795633/
https://ncbi.nlm.nih.gov/pubmed/19409973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2009.04.004
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