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Crystallization and preliminary X-ray analysis of aspartate transcarbamoylase from the parasitic protist Trypanosoma cruzi

Aspartate transcarbamoylase (ATCase), the second enzyme of the de novo pyrimidine-biosynthetic pathway, catalyzes the production of carbamoyl aspartate from carbamoyl phosphate and l-aspartate. In contrast to Escherichia coli ATCase and eukaryotic CAD multifunctional fusion enzymes, Trypanosoma cruz...

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Main Authors: Matoba, Kazuaki, Nara, Takeshi, Aoki, Takashi, Honma, Teruki, Tanaka, Akiko, Inoue, Masayuki, Matsuoka, Shigeru, Inaoka, Daniel Ken, Kita, Kiyoshi, Harada, Shigeharu
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795605/
https://ncbi.nlm.nih.gov/pubmed/19724137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109031959
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