Sequence requirements for cleavage activation of influenza virus hemagglutinin expressed in mammalian cells.
Cleavage of the hemagglutinin (HA) in tissue culture systems has been correlated with virulence of avian influenza viruses. To examine the structural requirements for cleavage of the HA, the HA gene from a virulent H5 influenza virus was expressed in mammalian cells (CV-1), and the cleavage site of...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1988
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279540/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829180/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.2.324 |
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