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Sequence requirements for cleavage activation of influenza virus hemagglutinin expressed in mammalian cells.

Cleavage of the hemagglutinin (HA) in tissue culture systems has been correlated with virulence of avian influenza viruses. To examine the structural requirements for cleavage of the HA, the HA gene from a virulent H5 influenza virus was expressed in mammalian cells (CV-1), and the cleavage site of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kawaoka, Y, Webster, R G
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279540/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829180/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.2.324
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