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Sequence requirements for cleavage activation of influenza virus hemagglutinin expressed in mammalian cells.

Cleavage of the hemagglutinin (HA) in tissue culture systems has been correlated with virulence of avian influenza viruses. To examine the structural requirements for cleavage of the HA, the HA gene from a virulent H5 influenza virus was expressed in mammalian cells (CV-1), and the cleavage site of...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Kawaoka, Y, Webster, R G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1988
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279540/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829180/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.2.324
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