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Sequence requirements for cleavage activation of influenza virus hemagglutinin expressed in mammalian cells.

Cleavage of the hemagglutinin (HA) in tissue culture systems has been correlated with virulence of avian influenza viruses. To examine the structural requirements for cleavage of the HA, the HA gene from a virulent H5 influenza virus was expressed in mammalian cells (CV-1), and the cleavage site of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Kawaoka, Y, Webster, R G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1988
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279540/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829180/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.2.324
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