Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death

Here, we report the results of a quantitative high-throughput screen (qHTS) measuring the endocytosis and translocation of a β-lactamase-fused-lethal factor and the identification of small molecules capable of obstructing the process of anthrax toxin internalization. Several small molecules protect...

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Detalhes bibliográficos
Main Authors: Zhu, Ping Jun, Hobson, John P., Southall, Noel, Qiu, Cunping, Thomas, Craig J., Lu, Jiamo, Inglese, James, Zheng, Wei, Leppla, Stephen H., Bugge, Thomas H., Austin, Christopher P., Liu, Shihui
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier Ltd. 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795356/
https://ncbi.nlm.nih.gov/pubmed/19540764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.05.054
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