Constitutive activity of cannabinoid-2 (CB(2)) receptors plays an essential role in the protean agonism of (+)AM1241 and L768242

BACKGROUND AND PURPOSE: Cannabinoid-2 (CB(2)) receptor-selective agonists have shown anti-nociceptive activity in models of neuropathic and inflammatory pain, and the two agonists most widely used, (+/−)AM1241 [(2-iodo-5-nitrophenyl)-[1-(1-methylpiperidin-2-ylmethyl)-1H-indol-3-yl-methanone] and L76...

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Detalhes bibliográficos
Main Authors: Mancini, I, Brusa, R, Quadrato, G, Foglia, C, Scandroglio, P, Silverman, LS, Tulshian, D, Reggiani, A, Beltramo, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795250/
https://ncbi.nlm.nih.gov/pubmed/19552692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00154.x
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