In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB(2) receptor?

BACKGROUND AND PURPOSE: The CB(2) receptor has been proposed as a novel target for the treatment of pain, and CB(2) receptor agonists defined in in vitro assays have demonstrated analgesic activity in animal models. Based on its in vivo analgesic efficacy, AM1241 has been classified as a CB(2)-selec...

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Detalles Bibliográficos
Autores principales: Yao, B B, Mukherjee, S, Fan, Y, Garrison, T R, Daza, A V, Grayson, G K, Hooker, B A, Dart, M J, Sullivan, J P, Meyer, M D
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2006
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013801/
https://ncbi.nlm.nih.gov/pubmed/16894349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706838
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