In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB(2) receptor?

BACKGROUND AND PURPOSE: The CB(2) receptor has been proposed as a novel target for the treatment of pain, and CB(2) receptor agonists defined in in vitro assays have demonstrated analgesic activity in animal models. Based on its in vivo analgesic efficacy, AM1241 has been classified as a CB(2)-selec...

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Bibliographic Details
Main Authors: Yao, B B, Mukherjee, S, Fan, Y, Garrison, T R, Daza, A V, Grayson, G K, Hooker, B A, Dart, M J, Sullivan, J P, Meyer, M D
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2006
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013801/
https://ncbi.nlm.nih.gov/pubmed/16894349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706838
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