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Hematopoietic Immortalizing Function of the NKL-Subclass Homeobox Gene TLX1

Translocations resulting in ectopic expression of the TLX1 homeobox gene (previously known as HOX11) are recurrent events in human T-cell acute lymphoblastic leukemia (T-ALL). Transduction of primary murine hematopoietic stem/progenitor cells with retroviral vectors expressing TLX1 readily yields im...

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Main Authors: Zweier-Renn, Lynnsey A., Hawley, Teresa S., Burkett, Sandra, Ramezani, Ali, Riz, Irene, Adler, Rima L., Hickstein, Dennis D., Hawley, Robert G.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795049/
https://ncbi.nlm.nih.gov/pubmed/19862821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20725
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