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The DN2 Myeloid-T (DN2mt) Progenitor is a Target Cell for Leukemic Transformation by the TLX1 Oncogene

INTRODUCTION: Inappropriate activation of the TLX1 (T-cell leukemia homeobox 1) gene by chromosomal translocation is a recurrent event in human T-cell Acute Lymphoblastic Leukemia (T-ALL). Ectopic expression of TLX1 in murine bone marrow progenitor cells using a conventional retroviral vector effici...

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Main Authors: Zweier-Renn, Lynnsey A, Riz, Irene, Hawley, Teresa S, Hawley, Robert G
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191823/
https://ncbi.nlm.nih.gov/pubmed/25309961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2329-8820.1000105
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