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Factor VIII delivered by hematopoietic stem cell-derived B cells corrects the phenotype of hemophilia A mice
The main impediments to clinical application of hematopoietic stem cell (HSC) gene therapy for treatment of hemophilia A are the bone marrow transplant-related risks and the potential for insertional mutagenesis caused by retroviral vectors. To circumvent these limitations, we have adapted a nonmyel...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117307/ https://ncbi.nlm.nih.gov/pubmed/21264447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH10-11-0725 |
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