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Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine-seeking
BACKGROUND: The cystine-glutamate exchanger is down-regulated after chronic cocaine, resulting in reduced extracellular levels of nucleus accumbens glutamate. The importance of cocaine-induced loss of glutamate homeostasis is revealed by N-acetylcysteine restoring cystine-glutamate exchange and atte...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795043/ https://ncbi.nlm.nih.gov/pubmed/19717140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.07.018 |
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