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Restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats

Impaired glutamate homeostasis is a key characteristic of the neurobiology of drug addiction in rodent models and contributes to the vulnerability to relapse to drug seeking. Although disrupted astrocytic and presynaptic regulation of glutamate release has been considered to constitute with impaired...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Zhang, Lan-Yuan, Zhou, Yue-Qing, Yu, Zhi-Peng, Zhang, Xiao-Qin, Shi, Jie, Shen, Hao-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115336/
https://ncbi.nlm.nih.gov/pubmed/33514875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-021-00955-1
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