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Restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats

Impaired glutamate homeostasis is a key characteristic of the neurobiology of drug addiction in rodent models and contributes to the vulnerability to relapse to drug seeking. Although disrupted astrocytic and presynaptic regulation of glutamate release has been considered to constitute with impaired...

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Bibliografiske detaljer
Udgivet i:Neuropsychopharmacology
Main Authors: Zhang, Lan-Yuan, Zhou, Yue-Qing, Yu, Zhi-Peng, Zhang, Xiao-Qin, Shi, Jie, Shen, Hao-Wei
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115336/
https://ncbi.nlm.nih.gov/pubmed/33514875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-021-00955-1
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