Ceftriaxone Normalizes Nucleus Accumbens Synaptic Transmission, Glutamate Transport, and Export following Cocaine Self-Administration and Extinction Training

Decreased basal glutamate levels are observed in the rat nucleus accumbens (NA) core following cocaine self-administration. This disruption of glutamate homeostasis arises from a reduction in the export of glutamate via system x(C)(−) and is accompanied by a decrease in expression of xCT, the cataly...

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Autori principali: Trantham-Davidson, Heather, LaLumiere, Ryan T., Reissner, Kathryn J., Kalivas, Peter W., Knackstedt, Lori A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
Soggetti:
Brief Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465971/
https://ncbi.nlm.nih.gov/pubmed/22956831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1976-12.2012
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