A carregar...
Non-Specificity of Binding of γ-Secretase Modulators to the Amyloid Precursor Protein
Evidence has been presented (Kukar et al. 2008 Nature 453, 925–929) that certain γ–secretase modulators (GSMs) target the 99 residue C-terminal domain (C99) of the amyloid precursor protein, a substrate of γ-secretase, but not the protease complex itself. Here, NMR results demonstrate a lack of spec...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794937/ https://ncbi.nlm.nih.gov/pubmed/19928774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901839d |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|