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Extracellular Loops 2 and 4 of GLYT2 Are Required for N-Arachidonylglycine Inhibition of Glycine Transport

Concentrations of extracellular glycine in the central nervous system are regulated by Na(+)/Cl(−)-dependent glycine transporters, GLYT1 and GLYT2. N-Arachidonylglycine (NAGly) is an endogenous inhibitor of GLYT2 with little or no effect on GLYT1 and is analgesic in rat models of neuropathic and inf...

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Bibliografski detalji
Glavni autori: Edington, Amelia R., McKinzie, Audra A., Reynolds, Aaron J., Kassiou, Michael, Ryan, Renae M., Vandenberg, Robert J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794758/
https://ncbi.nlm.nih.gov/pubmed/19875446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017509
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