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Constitutive and Regulated Endocytosis of the Glycine Transporter GLYT1b Is Controlled by Ubiquitination

The glycine transporter GLYT1 regulates both glycinergic and glutamatergic neurotransmission by controlling the reuptake of glycine at synapses. Trafficking of GLYT1 to and from the cell surface is critical for its function. Activation of PKC down-regulates the activity of GLYT1 through a mechanism...

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Detalhes bibliográficos
Main Authors: Fernández-Sánchez, Enrique, Martínez-Villarreal, Jaime, Giménez, Cecilio, Zafra, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740574/
https://ncbi.nlm.nih.gov/pubmed/19473961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.005165
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