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Extracellular Loops 2 and 4 of GLYT2 Are Required for N-Arachidonylglycine Inhibition of Glycine Transport
Concentrations of extracellular glycine in the central nervous system are regulated by Na(+)/Cl(−)-dependent glycine transporters, GLYT1 and GLYT2. N-Arachidonylglycine (NAGly) is an endogenous inhibitor of GLYT2 with little or no effect on GLYT1 and is analgesic in rat models of neuropathic and inf...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794758/ https://ncbi.nlm.nih.gov/pubmed/19875446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017509 |
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