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Identification of a 3(rd) Na(+) Binding Site of the Glycine Transporter, GlyT2

The Na(+)/Cl(-) dependent glycine transporters GlyT1 and GlyT2 regulate synaptic glycine concentrations. Glycine transport by GlyT2 is coupled to the co-transport of three Na(+) ions, whereas transport by GlyT1 is coupled to the co-transport of only two Na(+) ions. These differences in ion-flux coup...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Subramanian, Nandhitha, Scopelitti, Amanda J., Carland, Jane E., Ryan, Renae M., O’Mara, Megan L., Vandenberg, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919009/
https://ncbi.nlm.nih.gov/pubmed/27337045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157583
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